The efficacy of imitrex nasal spray was unaffected by presence of aura; duration of headache prior to treatment; gender, age, or weight of the patient; or concomitant use of common migraine prophylactic drugs e.
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Significant elevation in blood pressureincluding hypertensive crisis with acute impairment of organ systemshas been reported on rare occasions in patients treated with 5-HT1 agonistsincluding patients without a history of hypertensionMonitor blood pressure in patients treated with ImitrexImitrex tablets are contraindicated in patients with uncontrolled hypertension.
Burningcrawlingitchingnumbnesspricklingpins and needlesor tingling feelings change in color vision change in hearing difficulty with concentrating drowsiness heartburn increased sensitivity of the eyes to sunlight joint pain muscle aching or cramping muscle stiffness or tightness swollen joints trouble sleeping.
Postmarketing reportsShortness of breathas part of hypersensitivity reactionRef]
Cerebral hemorrhagesubarachnoid hemorrhageand stroke have occurred with 5-HT1 treatmentsome have resulted in fatalitiesOne case of sumatriptan-induced cortical stroke has been reported in a patient with sagittal sinus thrombosisIn some casesit appears possible that the cerebrovascular events were primaryand the 5-HT1 agonist administered in the belief that presenting symptoms were due to migraine when they were notPatients with migraine may also be at an increased risk of certain cerebrovascular events such as strokehemorrhageand transient ischemic attacks.
Never use more than your recommended doseOveruse of migraine headache medicine can make headaches worseTell your doctor if the medicine seems to stop working as well in treating your migraine attacks.
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